Work

Supplementary Figures 1 - 5 from Oncogenic NRAS, Required for Pathogenesis of Embryonic Rhabdomyosarcoma, Relies upon the HMGA2–IGF2BP2 Pathway

Year: 2023

Type: supplementary-materials

Abstract: PDF file - 396K, HMGA1 mRNA is ubiquitously expressed (S1); HMGA2 is indispensable for rhabdomyosarcoma growth in vitro (S2); HMGA2 is indispensable for rhabdomyosarcoma growth in vivo (S3); IGF2BP2 is an important target of HMGA2 in rhabdomyosarcoma (S4); HMGA2 modestly regulates E2F pathway in rhabdomyosarcoma (S5).

DOI: 10.1158/0008-5472.22395972.v1

Authors: Zhizhong Li, Yunyu Zhang, Krishnan Ramanujan, Yan Ma, David G. Kirsch, David J. Glass

Language: English

Topic: Sarcoma Diagnosis and Treatment

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361895183

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