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Supplementary Figures 1 - 4 from The Steroid Receptor Coactivator-3 Is Required for the Development of Castration-Resistant Prostate Cancer

Year: 2023

Type: supplementary-materials

Abstract: PDF file - 410K, Supplementary Figure S1. SRC-3 knockout in prostate epithelial cells does not affect prostate morphogenesis during development. Supplementary Figure S2. Deletion of SRC-3 has no impact on tumor histology or cellular proliferation in non-castrated 12-week-old mice. Supplementary Figure S3. Immunohistochemistry for pRPS6 in prostate tumors of castrated PtenCKO and Pten3CKO mice. Supplementary Figure S4. SRC-3 deletion does not change AR protein level in tissue lysate and AR target genes.

DOI: 10.1158/0008-5472.22398240

Authors: Jean C-Y. Tien, Zhaoliang Liu, Lan Liao, Fen Wang, Yixiang Xu, Ye-Lin Wu, Niya Zhou, Michael Ittmann, Jianming Xu

Language: English

Topic: Prostate Cancer Treatment and Research

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361872917

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