Supplementary Figure 5 from Blocking Lactate Export by Inhibiting the Myc Target MCT1 Disables Glycolysis and Glutathione Synthesis
Year: 2023
Type: supplementary-materials
Abstract: PDF file - 142K, MCT1 inhibition blocks glycolysis in Burkitt lymphoma cells, without affecting the steady state levels of glycolytic enzymes. Schematic of glutathione (GSH) metabolism and levels of components of glutamylcysteine ligase (GCL) in Raji BL cells treated with SR13800.
Authors: Joanne R. Doherty, Chunying Yang, Kristen E.N. Scott, Michael D. Cameron, Mohammad Fallahi, Weimin Li, Mark A. Hall, Antonio L. Amelio, Jitendra K. Mishra, Fangzheng Li, Mariola Tortosa, Heide Marika Genau, Robert J. Rounbehler, Yunqi Lu, Chi V. Dang, K. Ganesh Kumar, Andrew A. Butler, Thomas D. Bannister, Andrea T. Hooper, Keziban Unsal-Kacmaz, William R. Roush, John L. Cleveland
Language: English
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4361895730