Supplementary Figure 8 from Blocking Lactate Export by Inhibiting the Myc Target MCT1 Disables Glycolysis and Glutathione Synthesis
Year: 2023
Type: supplementary-materials
Abstract: PDF file - 332K, Schematic of selection for SR13800 resistance in Raji BL cells and levels of MCT1, MCT4 and LDH in SR13800-resistant cells. Mitotracker green staining of Raji BL cells treated with SR13800 and metformin. Schematic of metabolic pathways that are disrupted by blocking lactate transport through MCT1.
Authors: Joanne R. Doherty, Chunying Yang, Kristen E.N. Scott, Michael D. Cameron, Mohammad Fallahi, Weimin Li, Mark A. Hall, Antonio L. Amelio, Jitendra K. Mishra, Fangzheng Li, Mariola Tortosa, Heide Marika Genau, Robert J. Rounbehler, Yunqi Lu, Chi V. Dang, K. Ganesh Kumar, Andrew A. Butler, Thomas D. Bannister, Andrea T. Hooper, Keziban Unsal-Kacmaz, William R. Roush, John L. Cleveland
Language: English
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4361895750