Supplementary Figure 4 from Blocking Lactate Export by Inhibiting the Myc Target MCT1 Disables Glycolysis and Glutathione Synthesis
Year: 2023
Type: supplementary-materials
Abstract: PDF file - 116K, Structure of the MCT1 inhibitors AR-C122982 (SR13800) and AR-C155858 (SR13801). Cell cycle analysis, viability, clonogenecity and lactate transport in the indicated cells treated with SR13800. Proliferation of MCF7 cells overexpressing MCT1 or MCT4.
Authors: Joanne R. Doherty, Chunying Yang, Kristen E.N. Scott, Michael D. Cameron, Mohammad Fallahi, Weimin Li, Mark A. Hall, Antonio L. Amelio, Jitendra K. Mishra, Fangzheng Li, Mariola Tortosa, Heide Marika Genau, Robert J. Rounbehler, Yunqi Lu, Chi V. Dang, K. Ganesh Kumar, Andrew A. Butler, Thomas D. Bannister, Andrea T. Hooper, Keziban Unsal-Kacmaz, William R. Roush, John L. Cleveland
Language: English
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4361895760
