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Supplementary Figure 6 from Metastasis Suppressor KISS1 Seems to Reverse the Warburg Effect by Enhancing Mitochondrial Biogenesis

Year: 2023

Type: supplementary-materials

Abstract: PDF file - 6436K, Supplemental Figure 6. PGC1alpha is essential for KISS1 suppression of invasion and migration. MelJuSoKFM cells were transfected with a control shRNA or an shRNA targeting PGC1α followed by evaluation of transwell invasion (left panel) and migration using a scratch assay (right panel). Representative images for migrating and invading cells are shown. Values are mean plus-minus SD of triplicate samples. P-values are based upon a two-sided Student's T-test; ***, p<0.001.

DOI: 10.1158/0008-5472.22400880.v1

Authors: Wen Liu, Benjamin H. Beck, Kedar S. Vaidya, Kevin T. Nash, Kyle P. Feeley, Scott W. Ballinger, Keke M. Pounds, Warren L. Denning, Anne R. Diers, Aimee Landar, Animesh Dhar, Tomoo Iwakuma, Danny R. Welch

Language: English

Topic: Mechanisms of cancer metastasis

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361895828

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