Work

Supplementary Figures S1-S5 from Therapeutic Targeting of BRCA1-Mutated Breast Cancers with Agents That Activate DNA Repair

Year: 2023

Type: supplementary-materials

Abstract: Supplementary Figures S1-S5. SUM149PT cell line meets the screening criteria (S1); A preliminary screen identified BrdU as a small-molecule positive control (S2); Optimization of conditions for HT-screening (S3); Validation of the HT screening protocol (S4); DNA repair-activating agents exhibit minimal cytotoxicity at concentrations that enhance BER of ODD (S5).

DOI: 10.1158/0008-5472.22404177.v1

Authors: Elizabeth Alli, David Solow-Cordero, Stephanie C. Casey, James M. Ford

Language: English

Topic: PARP inhibition in cancer therapy

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361896280

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