Supplementary Figures and Tables from Ubiquitous Release of Exosomal Tumor Suppressor miR-6126 from Ovarian Cancer Cells
Year: 2023
Type: supplementary-materials
Abstract: Supplementary Data includes Supplementary Figures 1-6 and Supplementary Tables 1-3. Supplementary Figure 1 shows microscopic images for the characterization of exosomes. Supplementary Figure 2 shows the qPCR results of miR-6126 overexpression in miR-6126 mimic treated ovarian cancer cells (HeyA8, HeyA8-MDR, Skkov3-ip1, SKOV3-TR) Supplementary Figure 3 shows western blotting and qPCR results that shows the ingibition of Integrin beta-1 expression at protein and mRNA level upon miR-6126 mimic treatment. Supplementary Figure 4 shows the size distribution graphs of exosomes isolated from CTL mimic, miR-6126 mimic , CTL inhibitor, miR-6126 inhibitor treated SKOV3-IP1 cells. Supplementary Figure 5 shows ITGB1 mRNA levels in different ovarian cancer exosomes. Supplementary Figure 6 shows in vivo down regulation of ITGB1. Supplementary Table 1 shows demographic information of ovarian cancer patients whose tissue samples used in quantification of miR-6126 expression. Supplementary Table 2 shows raw microarray data for miR-6126 Supplementary Table 3 shows z-score values for miR-6126 for each exosome and cell sample.
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4361897498