SUPPLEMENTARY Figures and Table from HDAC1 Upregulation by NANOG Promotes Multidrug Resistance and a Stem-like Phenotype in Immune Edited Tumor Cells
Year: 2023
Type: supplementary-materials
Abstract: Supplementary Figure 1. Immune-edited CaSki P3 cells showed a stem-like phenotype. Supplementary Figure 2. NANOG does not effect on acetylation of histone H4. Supplementary Figure 3. Expression of HDAC genes, and genes involved in negative regulators of MCL-1 protein by NANOG-HDAC1 axis. Supplementary Figure 4. The NANOG-HDAC1 axis controls immune-resistance, drug-resistance and stem-like property in multiple types of human cancer cells. Supplementary Figure 5. Generation of MDA-MB231 P3 immune-resistant cell lines. Supplementary Figure 6. Regulation of HAT genes by NANOG-HDAC1 axis. Supplementary Figure 7. Schematic interpretation of immune selection-mediated epigenetic change and implications of epigenetic therapy.
Language: English
Topic: Cancer Cells and Metastasis
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4361897998