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Supplementary Tables from Epigenomic Profiling Discovers Trans-lineage SOX2 Partnerships Driving Tumor Heterogeneity in Lung Squamous Cell Carcinoma

Year: 2023

Type: supplementary-materials

Abstract: ST1: Original sources for the cell lines used in this study. ST2: sgRNA sequences for CRISPR-Cas9 system and primers for quantitative reverse transcription PCR. ST3: Characteristics of human primary LUSC tumor specimens for immunohistochemistry. ST4: Gene loci for super-enhancers near transcriptional regulators shared by all the LUSC cell lines in 'classical' subgroup. ST5: Gene loci for super-enhancers with highest signals near transcriptional regulators in LK2 and NCI-H520 cells. ST6: Associations between gene signatures from DNp63-overexpressed LK2 model and those from human TCGA-LUSC dataset based on POU3F2/ TP63 expression.

DOI: 10.1158/0008-5472.22422126.v1

Authors: Takashi Sato, Seungyeul Yoo, Ranran Kong, Abhilasha Sinha, Prashanth Chandramani-Shivalingappa, Ayushi Patel, Maya Fridrikh, Osamu Nagano, Takashi Masuko, Mary Beth Beasley, Charles A. Powell, Jun Zhu, Hideo Watanabe

Language: English

Topic: Epigenetics and DNA Methylation

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361898429

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