Work

Figure S6 from BRD4 Levels Determine the Response of Human Lung Cancer Cells to BET Degraders That Potently Induce Apoptosis through Suppression of Mcl-1

Year: 2023

Type: other

Abstract: ZBC260 and dBET at low concentration ranges do not synergize with TRAIL in decreasing the survival of H460 cells, but do so at high concentration ranges, likely due to the inability to decrease c-FLIP and Mcl-1 at low concentrations

DOI: 10.1158/0008-5472.22423458.v1

Authors: Dan Zong, Jiajia Gu, Giovanna C. Cavalcante, Weilong Yao, Guojing Zhang, Shaomeng Wang, Taofeek K. Owonikoko, Xia He, Shi-Yong Sun

Language: English

Topic: Protein Degradation and Inhibitors

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361898743

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