Work

Figure S7 from BRD4 Levels Determine the Response of Human Lung Cancer Cells to BET Degraders That Potently Induce Apoptosis through Suppression of Mcl-1

Year: 2023

Type: other

Abstract: ZBC260 does not apparently decrease mouse body weights in both animal studies with lung cancer xenografts and PDXs and effectively modulates the levels of several protein markers in lung cancer PDXs

DOI: 10.1158/0008-5472.22423455.v1

Authors: Dan Zong, Jiajia Gu, Giovanna C. Cavalcante, Weilong Yao, Guojing Zhang, Shaomeng Wang, Taofeek K. Owonikoko, Xia He, Shi-Yong Sun

Language: English

Topic: Protein Degradation and Inhibitors

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361898760

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