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Supplementary Figure 6 from Ran Is a Potential Therapeutic Target for Cancer Cells with Molecular Changes Associated with Activation of the PI3K/Akt/mTORC1 and Ras/MEK/ERK Pathways

Year: 2023

Type: supplementary-materials

Abstract: PDF file - 725K, Ran silencing-induced apoptosis depends on the growth stimulation in MDA MB231 and A549 cells using MTT assay.Percentage of cell survival in (A) MDA MB231 and (B) A549 cells expressing various levels of Ran grown in different conditions as determined by MTT assay. Results are plotted as histograms showing the mean � SD from three independent experiments. Key; *, ** and *** represent p < 0.05, <0.01 and <0.001, respectively.

DOI: 10.1158/1078-0432.22445183.v1

Authors: Hiu-Fung Yuen, Ka-Kui Chan, Claire Grills, James T. Murray, Angela Platt-Higgins, Osama Sharaf Eldin, Ken O'Byrne, Pasi Janne, Dean A. Fennell, Patrick G. Johnston, Philip S. Rudland, Mohamed El-Tanani

Language: English

Topic: PI3K/AKT/mTOR signaling in cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361902965

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