Supplementary Figures S1 - S6 from Inhibition of Melanoma Growth by Small Molecules That Promote the Mitochondrial Localization of ATF2
Year: 2023
Type: supplementary-materials
Abstract: Supplementary Figures S1 - S6 - PDF file 945K, Supplementary Figure S1. Effect of select compounds on ATF2 nuclear-mitochondrial Translocation; Supplementary Figure S2. SBI-0089410 or SBI-0087702 do not affect the subcellular localization of Stat3 or beta-catenin. Supplementary Figure S3. The expression of ATF252E attenuates apoptosis induced by SBI-0089410 or SBI-0087702; Supplementary Figure S4. SBI-0089410 or SBI-0087702-induced inhibition of cell motility and cell death are reversed by the stable expression of ATF252E; Supplementary Figure S5. itochondrial potential changes induced by SBI-0089410 or SBI-0087702 in melanoma cells; Supplementary Figure S6. The effect of SBI-0089410 or SBI-0087702 on ATF2 phosphorylation, PKC translocation and activation, and the viability of PLX4032-resistant melanoma cell lines.
Language: English
Topic: Melanoma and MAPK Pathways
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4361903263