Work

Supplementary Methods from Cellular Uptake of Imatinib into Leukemic Cells Is Independent of Human Organic Cation Transporter 1 (OCT1)

Year: 2023

Type: supplementary-materials

Abstract: PDF file 65K, Supplementary methods including chemicals, generation of a cell line expressing OCT1 variant p.V408, transport studies using oocytes and cell lines, LC-MS-MS analysis of imatinib, RNA isolation and quantification, shRNA knockdown, flow cytometry and confocal laser scanning microscopy

DOI: 10.1158/1078-0432.22449923

Authors: Anne T. Nies, Elke Schaeffeler, Heiko van der Kuip, Ingolf Cascorbi, Oliver Bruhn, Michael Kneba, Christiane Pott, Ute Hofmann, Christopher Volk, Shuiying Hu, Sharyn D. Baker, Alex Sparreboom, Peter Ruth, Hermann Koepsell, Matthias Schwab

Language: English

Topic: Drug Transport and Resistance Mechanisms

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361908315

Cites: 6

Cited by:

Related to: 10