Supplementary Figure 5 from Dual CDK4/CDK6 Inhibition Induces Cell-Cycle Arrest and Senescence in Neuroblastoma
Year: 2023
Type: supplementary-materials
Abstract: Supplementary Figure 5 - PDF file 138K, CDK4/6 inhibition does not induce cytotoxicity in neuroblastoma. (A) Caspase 3/7 activation and (B) PARP cleavage were not observed in cell lines with demonstrated sensitivity to LEE011. SN38, a known cytotoxic agent, was used as a positive control
Authors: JulieAnn Rader, Mike R. Russell, Lori S. Hart, Michael S. Nakazawa, Lili T. Belcastro, Daniel Martinez, Yimei Li, Erica L. Carpenter, Edward F. Attiyeh, Sharon J. Diskin, Sunkyu Kim, Sudha Parasuraman, Giordano Caponigro, Robert W. Schnepp, Andrew C. Wood, Bruce Pawel, Kristina A. Cole, John M. Maris
Language: English
Subfield: Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4361908638