Supplementary Figure 2 from Frequent Mutational Activation of the PI3K-AKT Pathway in Trastuzumab-Resistant Breast Cancer
Year: 2023
Type: supplementary-materials
Abstract: PDF file - 1392K, PTEN IHC changes from pre-trastuzumab to post-trastuzumab samples. Depicted are photomicrographs of PTEN change from reduced to loss of expression: a) PTEN expression by IHC in the primary breast invasive carcinoma with reduced nuclear and cytoplasmic staining as compared to the adjacent normal stroma (200X); b) HE staining of the primary lesion (200X); c) PTEN complete loss of expression in the secondary invasive carcinoma with absence of any staining in the lesion as compared to the adjacent normal stroma (200X); d) HE staining of the secondary lesion (200X)
Language: English
Topic: HER2/EGFR in Cancer Research
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4361908671