Supplementary Figure 6 from T Lymphocytes Redirected against the Chondroitin Sulfate Proteoglycan-4 Control the Growth of Multiple Solid Tumors both In Vitro and In Vivo
Year: 2023
Type: supplementary-materials
Abstract: PDF file - 125K, Immunohistochemistry, flow cytometry and survival curve analysis of the melanoma xenograft model. Panel A illustrates the expression of CSPG4 in tumor samples (SENMA) isolated 30 days after infusion of either CAR.CSPG4+ T cells or control T cells. Panel B. FACs analysis to detect tumor cells and CD3+ T cells in tumor biopsy, blood and spleen collected from mice at day 30 post tumor (SENMA) injection. Panel C. Survival curve of the melanoma xenograft model. Data are representative of 15 control and treated mice. Log-rank test: p<0.0001.
Language: English
Topic: CAR-T cell therapy research
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4361908702