Supplementary Methods, Tables 1 - 4, Figures 1 - 10 from Tadalafil Augments Tumor Specific Immunity in Patients with Head and Neck Squamous Cell Carcinoma
Year: 2023
Type: supplementary-materials
Abstract: Supplementary Table 1: Change in immune response by treatment group and HPV status for analyzed cohort n=32. Supplementary Table 2: Change in immune response by treatment group and HPV status for intent to treat cohort. Supplementary Table 3: Baseline Characteristics of the Intent to treat population. Supplementary Table 4: Pre and post changes in immune response outcomes between treatment arms (Intent to Treat cohort n=40). Supplementary Table 5 Correlations among changes in immune response outcomes in analyzed cohort. Supplementary Figure 1: Additional graphs of immune parameters. Supplementary Figure 2: Change in immune response by treatment group and HPV status. Supplementary Figure 3: Graphic relationship between immune response measures. Supplementary Figure 4 and 5: Gating strategy for the MDSC phenotype in this study defined as CD14+ or CD15+/CD33+/HLA-DRint/low/IL-4Ra+ as well as co-expression of CD14+/CD15+/ CD33+/HLA-DRint/low/IL-4Ra+. Supplementary Figure 6: Outliers from DTH assay are graphed on a larger scale for visualization. Supplementary Figure 7: Study Schema. Supplementary Figure 8: Correlation of BMI with change in primary immune response outcomes. Supplementary Figure 9: Correlations of BSA with change in primary immune response outcomes. Supplementary Figure 10: Correlations of BSA with change in primary immune response outcomes.
Authors: Joseph A. Califano, Zubair Khan, Kimberly A. Noonan, Lakshmi Rudraraju, Zhe Zhang, Hao Wang, Steven Goodman, Christine G. Gourin, Patrick K. Ha, Carole Fakhry, John Saunders, Marshall Levine, Mei Tang, Geoffrey Neuner, Jeremy D. Richmon, Ray Blanco, Nishant Agrawal, Wayne M. Koch, Shanthi Marur, Donald T. Weed, Paolo Serafini, Ivan Borrello
Language: English
Topic: Head and Neck Cancer Studies
Subfield: Otorhinolaryngology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4361909484