Supplementary Figures S1-6 from TLR9-Targeted STAT3 Silencing Abrogates Immunosuppressive Activity of Myeloid-Derived Suppressor Cells from Prostate Cancer Patients
Year: 2023
Type: supplementary-materials
Abstract: Supplementary Figures S1-6. Supplementary Figure S1. The effect of the freezing/thawing procedure on CD15 and CD33 marker staining on human PBMCs. Supplementary Figure S2. Time- and plasma concentration-dependent restoration of STAT3 activity in previously frozen G-MDSCs. Supplementary Figure S3. Immune cell populations accumulating in peripheral blood of mCRPC patients. Supplementary Figure S4. Effect of docetaxel treatment on granulocytic MDSCs in mCRPC patients. Supplementary Figure S5. CD15HI granulocytic myeloid cells isolated from prostate cancer patients inhibit proliferation of allogeneic T cells. Supplementary Figure S6. Direct cytotoxic effect of CpG-STAT3 siRNA on patient derived granulocytic MDSCs.
Language: English
Topic: Immune cells in cancer
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4361915911