Work

Supplementary Figure 1 from IL15 Trispecific Killer Engagers (TriKE) Make Natural Killer Cells Specific to CD33+ Targets While Also Inducing Persistence, In Vivo Expansion, and Enhanced Function

Year: 2023

Type: supplementary-materials

Abstract: Supplementary Figure 1. To address the input of the IL-15 moiety on NK cell cytotoxicity, we compared the 161533 TriKE to equivalent molar concentrations of IL-15 or IL-15 plus 1633 BiKE. Activation markers were studied.

DOI: 10.1158/1078-0432.22457919.v1

Authors: Daniel A. Vallera, Martin Felices, Ron McElmurry, Valarie McCullar, Xianzheng Zhou, Joerg Uwe Schmohl, Bin Zhang, Alexander J. Lenvik, Angela Panoskaltsis-Mortari, Michael R. Verneris, Jakub Tolar, Sarah Cooley, Daniel J. Weisdorf, Bruce R. Blazar, Jeffrey S. Miller

Language: English

Topic: Immune Cell Function and Interaction

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361915912

Cites:

Cited by: 1

Related to: 10