Supplemental figures 1-5 from Hsp90 Inhibitor Ganetespib Sensitizes Non–Small Cell Lung Cancer to Radiation but Has Variable Effects with Chemoradiation
Year: 2023
Type: supplementary-materials
Abstract: Supplemental Figure 1. RPPA heat map of H460 cells treated with varying doses of radiation and ganetespib. Supplemental Figure 2. RPPA heat map of A549 cells treated with varying doses of radiation and ganetespib. Supplemental Figure 3. Western blot validation of some of the altered proteins seen on RPPA analysis in H460 cells. Supplemental Figure 4. The apoptosis indicated by Caspase cleavage in RPPA and western blot were confirmed by flow cytometry Annexin V analysis. Supplemental Figure 5. H460 xenograft recapitulated in vitro DNA damage and apoptosis results.
Authors: Yifan Wang, Hui Liu, Lixia Diao, Adam Potter, Jianhu Zhang, Yawei Qiao, Jing Wang, David A. Proia, Ramesh Tailor, Ritsuko Komaki, Steven H. Lin
Language: English
Topic: Heat shock proteins research
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4361917519