Supplemental Figure 3 from NEDD8 Inhibition Overcomes CKS1B-Induced Drug Resistance by Upregulation of p21 in Multiple Myeloma
Year: 2023
Type: supplementary-materials
Abstract: Supplemental Figure 3. Proliferation and viability in a p53-expressing MM cell line. A, Immuno blot for p53 and CKS1B in parental and CKS1B-overexpressing MM cell lines. B, Proliferation of parental and CKS1B-overexpressing MM cell lines upon mock treatment, treatment with MLN4924, or treatment with one of three concentrations of bortezomib. C, Titrated viability of parental and CKS1B-overexpressing MM cell lines upon treatment with different concentrations of MLN4924.
Authors: Junwei Huang, Yi Zhou, Gregory S. Thomas, Zhimin Gu, Ye Yang, Hongwei Xu, Guido Tricot, Fenghuang Zhan
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4361919947