Supplementary Figures 1-8 from Keap1–Nrf2 Interaction Suppresses Cell Motility in Lung Adenocarcinomas by Targeting the S100P Protein
Year: 2023
Type: supplementary-materials
Abstract: Supplementary Figures 1-8. Supplementary Figure 1: Stably expressing Keap1 by CL1-5 cells is accompanied by decreasing migratory and invasive abilities. Supplementary Figure 2: Manipulation of Keap1 expression (overexpression or knockdown) had no significant effect on the cell growth rate. Supplementary Figure 3: Keap1 suppresses the mobility of cancer cells. Supplementary Figure 4: Functional confirmation of Keap1 and Nrf2 expressions in CL1-0 and CL1-5 cells. Supplementary Figure 5: Cell proliferation was not affected by Nrf2 or S100P expression. Supplementary Figure 6: Representative IHC images of Nrf2 in lung cancer tissues from surgically resected specimens. Supplementary Figure 7: Keap1 regulates intra-pulmonary metastasis in a CL1-0 xenograft model. Supplementary Figure 8: Keap1 mediates the degradation of RhoA in CL1-5 cells.
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4361920371