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Figure S3 from PKCα Attenuates Jagged-1–Mediated Notch Signaling in ErbB-2–Positive Breast Cancer to Reverse Trastuzumab Resistance

Year: 2023

Type: other

Abstract: A. Expression of phosphorylated ErbB2, AKT1, and ERK1/1 proteins in response to lapatinib, LY294002, or U0126. B. Expression of PKCα and phosphorylated Serine in substrates by Western blotting in trastuzumab resistant and sensitive BT474 cells.

DOI: 10.1158/1078-0432.22461053.v1

Authors: Kinnari Pandya, Debra Wyatt, Brian Gallagher, Deep Shah, Andrew Baker, Jeffrey Bloodworth, Andrei Zlobin, Antonio Pannuti, Andrew Green, Ian O. Ellis, Aleksandra Filipovic, Jason Sagert, Ajay Rana, Kathy S. Albain, Lucio Miele, Mitchell F. Denning, Clodia Osipo

Language: English

Topic: HER2/EGFR in Cancer Research

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361920589

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