SI Figures from Myeloma Cell Dynamics in Response to Treatment Supports a Model of Hierarchical Differentiation and Clonal Evolution
Year: 2023
Type: other
Abstract: Supplementary Figure S1. Demonstration of exponential curves and corresponding linear curves after log-transforming the original data. Supplementary Figure S2. Baseline values for the analysis of disease dynamics during treatment. Supplementary Figure S3. Histograms of the days from treatment cessation until rebound for patients in the VISTA and APEX trials when defining rebound as any value {greater than or equal to} 20% pre-treatment baseline. Supplementary Figure S4. Histograms of the days from treatment cessation until rebound for patients in the VISTA and APEX trials when defining rebound as any value {greater than or equal to} pre-treatment baseline. Supplementary Figure S5. Histograms of the days from treatment cessation until rebound for patients in the VISTA MP and VISTA VMP cohorts when defining rebound as any value {greater than or equal to} 120% pre-treatment baseline. Supplementary Figure S6. Histogram of the deviation between scheduled visit and real visit dates during the trial. Supplementary Figure S7. The predictions of the differentiation hierarchy model of MM. Supplementary Figure S8. Nine representative examples of predictions of the clonal evolution model of MM. Supplementary Figure S9. Early M-protein rebound for the refractory patients in the VISTA and APEX trials.
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4361920909