Figure S4 from Protein Kinase C Epsilon Is a Key Regulator of Mitochondrial Redox Homeostasis in Acute Myeloid Leukemia
Year: 2023
Type: other
Abstract: Supplemental Figure 4. (A) Dot plot representations of OCI-AML3-expressing roGFP2 cells to evaluate glutathione or hydrogen peroxide (H2O2) redox potential in cytoplasmic or mitochondrial compartments. Each of the four roGFP2 stable cell lines were transduced with lentiviruses expressing CTRL shRNA or PKCε shRNA_1 or _2 and analyzed by flow cytometry 5 days after transduction. (B) Represents the individual experiments of the combined data presented in figure 2A. (**p{less than or equal to}0.01; ***p{less than or equal to}0.001; ****p<0.0001)
Authors: Daniela Di Marcantonio, Esteban Martinez, Simone Sidoli, Jessica Vadaketh, Margaret Nieborowska-Skorska, Anushk Gupta, Jake M. Meadows, Francesca Ferraro, Elena Masselli, Grant A. Challen, Michael D. Milsom, Claudia Scholl, Stefan Fröhling, Siddharth Balachandran, Tomasz Skorski, Benjamin A. Garcia, Prisco Mirandola, Giuliana Gobbi, Ramiro Garzon, Marco Vitale, Stephen M. Sykes
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4361925156