Work

Figure S1-S5 from Acquired Resistance of ER-Positive Breast Cancer to Endocrine Treatment Confers an Adaptive Sensitivity to TRAIL through Posttranslational Downregulation of c-FLIP

Year: 2023

Type: other

Abstract: Figure S1: Endocrine-resistant MCF-7 cells demonstrate sensitivity to TRAIL Figure S2: Endocrine-resistant CSCs demonstrate sensitivity to TRIAL. Figure S3: Primary-derived patient samples. Figure S4: Endocrine-resistant primary and PDX tumour cells are sensitive to TRAIL. Figure S5: Mechanism of endocrine-resistant tumour cell sensitivity to TRAIL.

DOI: 10.1158/1078-0432.22465277.v1

Authors: Luke Piggott, Andreia Silva, Timothy Robinson, Angelica Santiago-Gómez, Bruno M. Simões, Michael Becker, Iduna Fichtner, Ladislav Andera, Philippa Young, Christine Morris, Peter Barrett-Lee, Fouad Alchami, Marco Piva, Maria dM. Vivanco, Robert B. Clarke, Julia Gee, Richard Clarkson

Language: English

Topic: Breast Cancer Treatment Studies

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361926771

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