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Supplementary Movie S4 from PARP Inhibitor Upregulates PD-L1 Expression and Enhances Cancer-Associated Immunosuppression

Year: 2023

Type: supplementary-materials

Abstract: PARPi treatment enhances resistance to activated T-cell killing. Time-lapse video of 231 (Nuc-RFP) cells with olaparib treatment co-cultured with activated PBMCs taken using the IncuCyte Zoom microscope.

DOI: 10.1158/1078-0432.22467009.v1

Authors: Shiping Jiao, Weiya Xia, Hirohito Yamaguchi, Yongkun Wei, Mei-Kuang Chen, Jung-Mao Hsu, Jennifer L. Hsu, Wen-Hsuan Yu, Yi Du, Heng-Huan Lee, Chia-Wei Li, Chao-Kai Chou, Seung-Oe Lim, Shih-Shin Chang, Jennifer Litton, Banu Arun, Gabriel N. Hortobagyi, Mien-Chie Hung

Language: English

Topic: PARP inhibition in cancer therapy

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361929684

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