Figure S2 from Single-Cell Analyses of Prostate Cancer Liquid Biopsies Acquired by Apheresis
Year: 2023
Type: other
Abstract: Summary of the validation steps. a) Male vs female: Genome plot of amplified male DNA vs amplified female DNA using the Ampli 1 kit. b) WBC vs WBC: Genomic profile of Ampli1 amplified WBCs against another WBC. c) Dilution evaluation: Genomic aberrations of an mCRPC sample with known CNA diluted serially to 10ng/µL, 1ng/µL, 0.1ng/µL, and 0.03ng/µL with all dilutions generating similar profiles after Ampli1TM WGA and aCGH. Gains and amplification depicted in blue, and losses and homozygous/deep deletion in red.
Authors: Maryou B. Lambros, George Seed, Semini Sumanasuriya, Veronica Gil, Mateus Crespo, Mariane Fontes, Rob Chandler, Niven Mehra, Gemma Fowler, Berni Ebbs, Penny Flohr, Susana Miranda, Wei Yuan, Alan Mackay, Ana Ferreira, Rita Pereira, Claudia Bertan, Ines Figueiredo, Ruth Riisnaes, Daniel Nava Rodrigues, Adam Sharp, Jane Goodall, Gunther Boysen, Suzanne Carreira, Diletta Bianchini, Pasquale Rescigno, Zafeiris Zafeiriou, Joanne Hunt, Deirdre Moloney, Lucy Hamilton, Rui P. Neves, Joost Swennenhuis, Kiki Andree, Nikolas H. Stoecklein, Leon W.M.M. Terstappen, Johann S. de Bono
Language: English
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4361932607