Supplementary Information from TMPRSS2-ERG Controls Luminal Epithelial Lineage and Antiandrogen Sensitivity in PTEN and TP53-Mutated Prostate Cancer
Year: 2023
Type: supplementary-materials
Abstract: Supplementary Figures and Tables. /// Supplementary Figure 1. TP53 mutation status in human prostate cancer. /// Supplementary Figure 2. Genotypic and histological characterization of Pten/Trp53/ERG-altered mouse prostates. /// Supplementary Figure 3. Immunohistochemistry and immunofluorescent co-staining of key markers in serially-sectioned mouse prostate tissues. /// Supplementary Figure 4. Transcriptomic characterization of the Pten/Trp53/ERG-mutated mouse prostates. /// Supplementary Figure 5. Western blot analysis of expression of ERG downstream genes and E2F1 targets in human prostate cancer cells. /// Supplementary Figure 6. Analysis of expression of ERG-regulated genes and ERG chromatin binding at these gene loci in human prostate cancer PC-3 cells. /// Supplementary Figure 7. Palbociclib and enzalutamide treatment optimization in human prostate cancer cell lines. /// Supplementary Figure 8. Characterization of LNCaP-RF xenografts and mouse tumor-derived allografts. /// Supplementary Table 1. shRNA sequences. /// Supplementary Table 2. RT-qPCR primer sequences. /// Supplementary Table 3. ChIP-qPCR primer sequences. /// Supplementary Table 4. PCR genotyping primer sequences. /// Supplementary Table 5. Raw staining index scores for AR and ERG IHC of mCRPC human tissue microarray. /// References
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4361933182