Supplementary Data from Loss of Function of DOCK4 in Myelodysplastic Syndromes Stem Cells is Restored by Inhibitors of DOCK4 Signaling Networks
Year: 2023
Type: supplementary-materials
Abstract: Supplemental figure 3: Twenty four hours post DOCK4 siRNA nucleofection into TF1 cells, A) Control and DOCK4 knockdown TF1 cells were subjected to in vitro transwel migration assay. Data are represented as mean {plus minus}SEM from two technical replicates (*P < 0.05; Student's t test). Representative data from two independent experiments are shown. B) Control and DOCK4 knocked down TF1 cells were stained for actin and analyzed by immunofluorescence microscopy. Cells which depicted spread morphology with bundled actin at the leading edges were marked by white arrows (Scale bar, 15μM). Individual cells at high magnification showing cell spreading and bundled F-actin when DOCK4 levels were reduced.
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4361934824