Supplementary Figure 10 from Somatic Epigenetic Silencing of RIPK3 Inactivates Necroptosis and Contributes to Chemoresistance in Malignant Mesothelioma
Year: 2023
Type: supplementary-materials
Abstract: Expression levels of MLKL, CASP8 and FADD were not significantly correlated with MM patient survival. Data are from TCGA dataset of 87 primary pleural MM patients. A, C and E, Box plots of mRNA expression of MLKL, CASP8 and FADD where each X-axis shows quartile-based mRNA expression categories, and each Y-axis indicates the log-transformed RSEM mRNA expression values. In box plots, color code orange indicates high gene expression, and blue indicates low expression. B, D and F, Kaplan-Meier curves indicating OS of MM patients based on mRNA expression of MLKL, CASP8 and FADD, with MM patients having low expression of each gene shown with blue line and MM patients with high levels of expression of each of gene shown with an orange line.
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4361936165