Work

Supplementary Figures S1-S9 from Whole-Genome Sequencing of Common Salivary Gland Carcinomas: Subtype-Restricted and Shared Genetic Alterations

Year: 2023

Type: supplementary-materials

Abstract: Fig. S1. Difference in mean age and in mean tumor size among subtypes. Fig. S2. Genes effected by putative somatic Mobile Elements Insertions (MEI) events. Fig. S3. Rearrangements leading to potential fusion events. Fig. S4. Mutational hotspots in CIC (SLC25A1) and MUC16 genes. Fig. S5. Contribution of known somatic mutation signatures into mutational processes. Fig. S6. Genes effected by frequent germline alterations. Fig. S7. Association of patient's age (A) and each subtype (B) with survival. Fig. S8. Association of each type of structural variations (SVs) and overall survival. Fig. S9. CCDC58 mutation associated with worse survival.

DOI: 10.1158/1078-0432.22481042.v1

Authors: Tatiana V. Karpinets, Yoshitsugu Mitani, Bin Liu, Jianhua Zhang, Kristen B. Pytynia, Linton D. Sellen, Danice T. Karagiannis, Renata Ferrarotto, Andrew P. Futreal, Adel K. El-Naggar

Institution: The University of Texas MD Anderson Cancer Center

Language: English

Topic: Salivary Gland Tumors Diagnosis and Treatment

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361939594

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