Work

Data from Molecular Targeting of Neural Cancer Stem Cells: TTAGGG, You're It!

Year: 2023

Type: other

Abstract: Telomerase is an important mechanism by which cancers escape replicative senescence. In neural tumors, cancer stem cells express telomerase, suggesting that this may explain their preferential tumorigenesis. Oligonucleotide telomerase targeting selectively disrupts cancer stem cell growth through the induction of differentiation, adding to the armamentarium of anticancer stem cell therapies. Clin Cancer Res; 17(1); 3–5. ©2011 AACR.

DOI: 10.1158/1078-0432.c.6519627

Authors: Anita B. Hjelmeland, Jeremy N. Rich

Institutions: Cleveland Clinic, Cleveland Clinic Lerner College of Medicine

Language: English

Topic: Telomeres, Telomerase, and Senescence

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361944061

Cites: 10

Cited by:

Related to: 10