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Data from Therapeutic Oligonucleotides: The Road Not Taken

Year: 2023

Type: other

Abstract: Antisense oligonucleotide therapeutics have been in development for almost 25 years without a single U.S. Food and Drug Administration–approved product in cancer. The reasons for this absence stem, in part, from a deep lack of understanding about how to deliver these molecules to cancer cells in vivo. Clin Cancer Res; 17(20); 6369–72. ©2011 AACR.

DOI: 10.1158/1078-0432.c.6520170.v1

Authors: Cy A. Stein, Sanjay Goel

Language: English

Topic: RNA Interference and Gene Delivery

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361950192

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