Supplementary Figure S1 from Whole-exome Sequencing in Penile Squamous Cell Carcinoma Uncovers Novel Prognostic Categorization and Drug Targets Similar to Head and Neck Squamous Cell Carcinoma
Year: 2023
Type: supplementary-materials
Abstract: Figure S1 - Oncogenic pathways enrichment among penile cancer samples. Each oncoplot represent the mutation distribution among PSCC samples for each of the 10 oncogenic signaling pathways (RTK/RAS pathway; Wnt pathway; Notch pathway; Hippo pathway; PI3K pathway; Cell cycle pathway; Myc pathway; TGFβ pathway; p53 pathway; and Nrf2 pathway) described by Sanchez-Vega et al. (2018). Each oncoplot represents the list of specific genes linked to pathways with major impact on cancer curated by Sanchez-Vega et al. (2018) that were found mutated in our PSCC samples. Colored squares indicate mutant samples and the respective gene. Red gene symbols indicate known oncogenes and blue gene symbols indicate known tumor suppressor genes. Patient distribution along the X-axis is the same observed in the oncoplot of the Figure 1.
Language: English
Topic: Genital Health and Disease
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4361961652