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Supplementary Figures 1-5 from Anti-DLL4 Has Broad Spectrum Activity in Pancreatic Cancer Dependent on Targeting DLL4-Notch Signaling in Both Tumor and Vasculature Cells

Year: 2023

Type: supplementary-materials

Abstract: PDF file - 139K, Figure S1. DLL4 expression in pancreatic tumor xenografts relative to normal human pancreas. Figure S2. Effect of anti-DLL4 on growth of orthotoptically implanted pancreatic xenograft tumors. Figure S3. Individual tumor measurements for In Vivo Limiting Dilution Assay. Figure S4. Effect of anti-hDLL4, anti-mDLL4, anti-DLL4 and gemcitabine on EMT marker expression

DOI: 10.1158/1078-0432.22451198.v1

Authors: Wan-Ching Yen, Marcus M. Fischer, Mark Hynes, Jingjiang Wu, Edward Kim, Lucia Beviglia, V. Pete Yeung, Xiaomei Song, Ann M. Kapoun, John Lewicki, Austin Gurney, Diane M. Simeone, Timothy Hoey

Language: English

Topic: Pancreatic and Hepatic Oncology Research

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361968440

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