Supplementary Figures 1 - 9 from Darinaparsin: Solid Tumor Hypoxic Cytotoxin and Radiosensitizer
Year: 2023
Type: supplementary-materials
Abstract: PDF file, 1660KB, S1 Mouse body weight change in response to DPS treatment; S2. DPS did not induce autophagy in HI-LAPC-4 cells; S3: DPS did not induce cell cycle arrest; S4: DPS did not enhance IR-induced DNA damage; S5: DPS activity on solid tumor cells was not dependent on mitochondrial damage; S6: DPS cytotoxicity depends partially on protein synthesis; S7: DPS did not modulate HIF1α protein and transcriptional activity; Fig S8: JNK was activated by DPS, but not required for DPS cytotoxicity; S9: Oncogene RAS and MYC were overexpressed in HI-LAPC-4 and PC-3 cancer cells.
Authors: Junqiang Tian, Hongjuan Zhao, Rosalie Nolley, Stephen W. Reese, Sarah R. Young, Xuejun Li, Donna M. Peehl, Susan J. Knox
Language: English
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4361968443