Supplemental Files from Alternatively-Activated Macrophages Upregulate Mesothelial Expression of P-Selectin to Enhance Adhesion of Ovarian Cancer Cells
Year: 2023
Type: supplementary-materials
Abstract: Supplemental File contains 8 Figures: SF1 shows a schematic of the co-culture device, SF2 shows additional details of PLSR model and validation of MIP-1β, SF3 shows validation of MIP-1β impact on SELP/P-selectin in mesothelial cell lines, SF4 shows CD24 expression in HGSOC lines, SF5 shows additional CD24 data for HGSOC lines and validation of CD24 siRNA knockdown, SF6 shows additional IHC of in vivo tissues for P-selectin, SF7 shows the impact of ascites on additional HGSOC lines, and SF8 shows additional immunofluorescent images of P-selectin in HGSOC patients. There are also 4 Tables: ST1 lists genes differentially expressed in LP-9 with AAM co-culture, ST2 lists soluble factors in Bioplex arrays that were not detected, ST3 provides CCR1 and CCR5 qRT-PCR results, and ST4 details the prognostic impact of CD24 in HGSOC patients.
Language: English
Topic: Immune cells in cancer
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4361968996