Supplemental Figures and Table 1 from Integrated Genomic Analysis of Pancreatic Ductal Adenocarcinomas Reveals Genomic Rearrangement Events as Significant Drivers of Disease
Year: 2023
Type: supplementary-materials
Abstract: Supplemental Table 1 and Figures 1-5 combined in single PDF file. Supplemental Table 1: Mate Pair sequencing data statistics. Supplemental Figure 1: KRAS Mutations in PDAC tumors. Supplemental Figure 2: Frequency copy number plots at the SMAD4 locus (A), chromosome 18 (B), FHIT (C), ZNF521 (D) loci in the primary PDAC tumors and for SMAD4, FHIT and ZNF521 in the PDX tumors (E). Supplemental Figure 3: Expression level changes of commonly hit genes. Supplemental Figure 4: TGFbeta responsive genes. Supplemental Figure 5: FHIT pathway genes and signaling networks.
Authors: Stephen J. Murphy, Steven N. Hart, Geoffrey C. Halling, Sarah H. Johnson, James B. Smadbeck, Travis Drucker, Joema Felipe Lima, Fariborz Rakhshan Rohakhtar, Faye R. Harris, Farhad Kosari, Subbaya Subramanian, Gloria M. Petersen, Timothy D. Wiltshire, Benjamin R. Kipp, Mark J. Truty, Robert R. McWilliams, Fergus J. Couch, George Vasmatzis
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4361973385