Work

Supplementary Figures 1 - 4 from Targeting the Transposase Domain of the DNA Repair Component Metnase to Enhance Chemotherapy

Year: 2023

Type: supplementary-materials

Abstract: PDF file - 670K, Figure S1. The composite approach for in silico compound selection. Figure S2. Superposition of the 3D structures of Metnase (model, blue) and MOS-1 active sites (2F7T, orange). Figure S3. Comparison between two metnase structures Figure S4. Electrostatic surface of the metnase Transposase domain.

DOI: 10.1158/0008-5472.22392029

Authors: Elizabeth A. Williamson, Leah Damiani, Andrei Leitao, Chelin Hu, Helen Hathaway, Tudor Oprea, Larry Sklar, Montaser Shaheen, Julie Bauman, Wei Wang, Jac A. Nickoloff, Suk-Hee Lee, Robert Hromas

Language: English

Topic: Computational Drug Discovery Methods

Subfield: Computational Theory and Mathematics

Field: Computer Science

Domain: Physical Sciences

Open Access status: gold

OpenAlex ID: W4362238941

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