Work

Supplemental Figure 1 from EGF Receptor Promotes Prostate Cancer Bone Metastasis by Downregulating miR-1 and Activating TWIST1

Year: 2023

Type: supplementary-materials

Abstract: (A and B) GSEA showed enrichment of two prostate cancer datasets, MSKCC (A) and TCGA (B), with EGFR signaling downregulation-responsive genes in cancers expressing high levels of miR-1. NES, normalized enrichment score; FDR, false discovery rate. (C and D) Mean expression of miR-1 for signatures separated on the basis of up- and downregulated EGFR signaling-responsive genes in the MSKCC (C) and TCGA (D) datasets.

DOI: 10.1158/0008-5472.22406165

Authors: Yung-Sheng Chang, Wei-Yu Chen, Juan Juan Yin, Heather Sheppard-Tillman, Jiaoti Huang, Yen-Nien Liu

Language: English

Topic: MicroRNA in disease regulation

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362295019

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