Supplementary Figures S1-7 from GON4L Drives Cancer Growth through a YY1–Androgen Receptor–CD24 Axis
Year: 2023
Type: supplementary-materials
Abstract: Figure S1 - Expression pattern of CD24 in different cell lines used and effect of candidate gene depletion on CD24 protein levels. Figure S2 - siRNA dose-dependent GON4L knockdown and STRING analysis for GON4L interactions. Figure S3 - Effect of YY1 knockdown on GON4L mRNA levels. Figure S4 - Effect of GON4L and YY1 knockdown on tumor growth in vivo and their expression in bladder cancer. Figure S5 - Luciferase reporter assays in control plasmids, endogenous CO-IP for AR and YY1 interaction, and effect of GON4L and YY1 knockdown on AR expression. Figure S6 - AR expression levels in different cancer cell lines, and GON4L and YY1 knockdown as measured by qRT-PCR. Figure S7 - GON4L and YY1 knockdown in AR- cancer cell lines.
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4362320271