Work

Supplementary Figure 3 from Helicase-Driven Activation of NFκB-COX2 Pathway Mediates the Immunosuppressive Component of dsRNA-Driven Inflammation in the Human Tumor Microenvironment

Year: 2023

Type: supplementary-materials

Abstract: IFNα enhances the response to TLR3 triggering by either poly-I:C or rintatolimod, but prostaglandin inhibition is selectively needed to optimize the pattern of inflammation induced by poly-I:C.

DOI: 10.1158/0008-5472.22418859

Authors: Marie-Nicole Theodoraki, Saigopalakrishna Yerneni, Saumendra N. Sarkar, Brian Orr, Ravikumar Muthuswamy, Jamie Voyten, Francesmary Modugno, Weijian Jiang, Melissa Grimm, Per H. Basse, David L. Bartlett, Robert P. Edwards, Pawel Kalinski

Language: English

Topic: Immune Response and Inflammation

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362352483

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