Work

Figure S2 from Deoxycytidine Release from Pancreatic Stellate Cells Promotes Gemcitabine Resistance

Year: 2023

Type: other

Abstract: Fig. S2. N-acetyl alanine does not protect from gemcitabine toxicity and nucleoside levels in PDAC cells are not effected by treatment with gemcitabine or conditioned media (A) Dose response curves with N-acetyl-alanine without (solid lines) or with (dashed lines) 0.025 uM gemcitabine. The viability after treatment with PSC2 CM is also shown. Data show three biological replicates +/- SEM. (B-E) Absolute quantification of the indicated species in within PDAC cells after the indicated treatment. Data show 3 biological replicates +/- SEM.

DOI: 10.1158/0008-5472.22422687

Authors: Simona Dalin, Mark R. Sullivan, Allison N. Lau, Beatrice Grauman-Boss, Helen S. Mueller, Emanuel Kreidl, Silvia Fenoglio, Alba Luengo, Jacqueline A. Lees, Matthew G. Vander Heiden, Douglas A. Lauffenburger, Michael T. Hemann

Language: English

Topic: Pancreatic and Hepatic Oncology Research

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362363162

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