Work

Supplementary Figure 4 from Pharmacokinetic and Pharmacodynamic Analysis of Circulating Biomarkers of Anti-NRP1, a Novel Antiangiogenesis Agent, in Two Phase I Trials in Patients with Advanced Solid Tumors

Year: 2023

Type: supplementary-materials

Abstract: PDF file, 51K, Ratio to baseline for plasma VEGF from the days 2 or 28 time points for all animals administered a single dose of MNRP1685A at varying dose levels. Each dose level contained n=4 animals. Plasma VEGF was measured using an MSD assay.

DOI: 10.1158/1078-0432.22447685

Authors: Yan Xin, Jessica Li, Jenny Wu, Rashell Kinard, Colin D. Weekes, Amita Patnaik, Patricia LoRusso, Rainer Brachmann, Raymond K. Tong, Yibing Yan, Ryan Watts, Shuang Bai, Priti S. Hegde

Language: English

Topic: Angiogenesis and VEGF in Cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362394540

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