Supplementary Methods, Schemes 1 - 2, Figures 1 - 2, Tables 1 - 2 from Targeted Delivery of Paclitaxel to EphA2-Expressing Cancer Cells
Year: 2023
Type: supplementary-materials
Abstract: PDF file - 328K, Scheme 1. Synthesis of YNH motif and dYNH motif Scheme S2. Synthetic route for YSA-PTX Figure S1. In vivo prostate cancer xenograft studies. Figure S2. EphA2 expression in RENCA renal carcinoma cells and PC3M prostate cancer cells. Supplemental Table 1. Athymic nude mice bearing pre-established subcutaneous PC3M tumors (230 mm3 average volume) were treated three times weekly for a period of 18 days (8 total injections) with intravenous doses of vehicle (CT), PTX (10 mg/Kg) and DYP-PTX or YSA-PTX (at a dose equimolar to the taxol dose).
Authors: Si Wang, Roberta Noberini, John L. Stebbins, Swadesh Das, Ziming Zhang, Bainan Wu, Sayantan Mitra, Sandrine Billet, Ana Fernandez, Neil A. Bhowmick, Shinichi Kitada, Elena B. Pasquale, Paul B. Fisher, Maurizio Pellecchia
Language: English
Subfield: Biomaterials
Field: Materials Science
Domain: Physical Sciences
Open Access status: gold
OpenAlex ID: W4362395024