Supplemental Figures from Fluorescent Image–Guided Surgery with an Anti-Prostate Stem Cell Antigen (PSCA) Diabody Enables Targeted Resection of Mouse Prostate Cancer Xenografts in Real Time
Year: 2023
Type: supplementary-materials
Abstract: Figure S1. Biochemical characterization of Cy5 conjugated anti-PSCA cys-Diabody. Figure S2. Validation of in vivo tumor detection using endogenously PSCA-expressing line LAPC-9 Figure S3. Determining the optimal time point for in vivo Cy5-cDb imaging. Figure S4. Cy5-cDb enabled fluorescence-guided surgical resection of PSCA-expressing tumors. Figure S5. LAPC-9 intramuscular tumor extent was not readily detectable under white light (A-B), but was clearly visible under fluorescence guidance (C). Figure S6. Intraoperative white light and florescent images of 22Rv1 intramuscular xenografts utilizing anti-PSCA Cy5-cDb. Figure S7. Additional H&E histopathology of tumor margins from the prospective, randomized trial.
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4362396800