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Supplementary Figures 1-2 from K562-Derived Whole-Cell Vaccine Enhances Antitumor Responses of CAR-Redirected Virus-Specific Cytotoxic T Lymphocytes In Vivo

Year: 2023

Type: supplementary-materials

Abstract: Supplementary Figures 1-2. Supplementary Figure 1. Expression of CD80, CD83, CD11c and HLA-DR by monocytes 72 hours after co-culture with irradiated K/pp65 (in blue), K/OX40L/pp65 (in violet), K/CD40L/pp65 (in orange) and K/OX40L/CD40L/pp65 (in green); Supplementary Figure 2. Cytotoxic activity (51Cr-release assay at 40:1, 20:1, 10:1 and 5:1 effector:target ratios) of CAR-CMV-CTLs stimulated in vitro by K/pp65 or K/CD40L/pp65 or K/CD40L/OX40L/pp65.

DOI: 10.1158/1078-0432.22457898

Authors: Ignazio Caruana, Gerrit Weber, Brandon C. Ballard, Michael S. Wood, Barbara Savoldo, Gianpietro Dotti

Language: English

Topic: Immunotherapy and Immune Responses

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361917163

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